The film is based on the novel of the same name by James Fenimore Cooper. The middle of the XVIII century. The colonial division of North America continues. The struggle of Britain and France for territorial domination divided and made enemies of the Indian tribes and European settlers. Raised by the Indians, St. John’s Wort (Lex Barker), along with his blood brother Chingachgook, tries to save the two girls living with their father in a small fort on the river, from the attack of the hostile Huron tribe.